Hi all,
Just wanted to give a quick write-up of my microdosing experience. TLDR at the bottom.
I'm a male in my late 20s with generalized anxiety disorder. My anxiety doesn't seem to be trauma-based or triggered by anything in particular; I'll just wake up and feel anxious for a few days. It's frustrating because there is no discernible cause, and therefore, I just deal with it.
Four years ago, I started taking 10mg of escitalopram (Lexapro), which was great. A few months later, I started 150mg of bupropion (Wellbutrin) to help with some of the sexual side effects associated with SSRIs.
Honestly, this combo worked well. While I still had anxiety (I believe you can never truly get rid of it), the waves of anxiety were a lot less frequent and intense.
Recently, I was able to acquire access to .2-.3mg of Golden Teacher psilocybin capsules (verified). I tested the potency of the capsules and was able to trip pretty hard. I dabbled in psilocybin and LSD in college and always had great experiences with both. I figured I might as well try microdosing.
I started dosing every other day and tapering off my Lexapro. I tapered off too fast from the SSRI and had a pretty rough time. For a few weeks, it felt like my brain was just not working. It's hard to describe, but it was very unpleasant.
Luckily, I pushed through the withdrawals and was finally off Lexapro for the first time in four years. I was still taking the Wellbutrin but had planned on tapering off as well.
After a month and a half of microdosing, I'm discontinuing my little experiment and going back to my Lexapro. I just don't feel like it worked for me.
I feel anxious, on edge, my mind races, I overthink, etc.
The hypothesized link to psilocybin and valvular heart disease spooks me too.
Anyway, I just wanted to share my experience in case someone goes through something similar. For anyone considering microdosing, I'd recommend trying it for sure! Just don't go thinking it's an end-all cure for anxiety.
Open to any questions, comments, or feedback, so let me know.
TLDR: Tried microdosing psilocybin for anxiety to replace Lexapro. Didn't work for me, ended up feeling worse. Back on Lexapro now. Microdosing might work for others, but it's not a guaranteed solution for anxiety.